Vanderbilt Institute for Infection Immunology and Inflammation (VI4)

October 31, 2019

Imaging host-pathogen battle for metal

An unprecedented view of bacterial products within infected tissues opens new opportunities to explore infection biology and devise novel therapeutic strategies.

By Leigh MacMillan
October 8, 2019

New leadership appointments for Pathology, Microbiology and Immunology

By Bill Snyder
bacteria microbiome
April 11, 2019

How bugs overcome host defenses

Vanderbilt researchers led by Eric Skaar are probing the mechanisms bacteria use when faced with nutrient starvation — a host defense strategy called “nutritional immunity.”

By Leigh MacMillan
June 28, 2018

New staph virulence factor

Jun. 28, 2018—The new factor, an enzyme involved in host-pathogen interactions, may be a viable target for treating staph infections.

By Leigh MacMillan
March 15, 2018

New imaging approach offers unprecedented views of staph infection

A new integrated imaging approach makes it possible to probe the molecules involved in invasive infections and can be broadly applied to any health or disease state.

By Leigh MacMillan
conceptual - glowing cell
January 11, 2018

Lighting up iron levels

A new probe enables iron imaging in living animals, providing a unique tool for studying iron’s contributions to health and disease.

By Leigh MacMillan
November 20, 2017

15 faculty members elected as AAAS fellows

Fifteen Vanderbilt faculty members conducting a range of biomedical and clinical research have been elected fellows of the American Association for the Advancement of Science. Six of the 15 have received funding through the university’s Trans-Institutional Programs initiative, which facilitates research and teaching collaborations across disciplines and are a core pillar of the university’s Academic Strategic Plan.
By Bill Snyder
September 21, 2017

Excess dietary manganese increases risk of staph infection in heart

Too much dietary manganese — an essential trace mineral found in leafy green vegetables, fruits and nuts — promotes infection of the heart by the bacterium Staphylococcus aureus (“staph”).
By Leigh MacMillan
July 27, 2017

Investigators use light to kill microbial ‘vampires’

On July 24 Vanderbilt scientist Eric Skaar, Ph.D., MPH, summarized his group’s latest paper in a tweet: “If S. aureus is going to drink our blood like a vampire, let's kill it with sunlight.”
By Bill Snyder
June 29, 2017

New institute to focus on immune system

Vanderbilt University Medical Center (VUMC) is launching a new institute to coordinate initiatives among the rapidly evolving disciplines of infection biology, immunology and inflammatory diseases.
By Bill Snyder
November 3, 2016

VUMC investigators find pathogens work together to infect host

Pseudomonas aeruginosa and Staphylococcus aureus — two pathogens that frequently co-infect the lungs of patients with cystic fibrosis — appear to cooperate with each other, Vanderbilt investigators have discovered. When pseudomonas is starved for metal by the host, it shuts down the production of factors that would normally kill staph, promoting a co-infection.
By Leigh MacMillan
September 26, 2016

Study shows excess dietary zinc worsens C. diff infection

Too much dietary zinc increases susceptibility to infection by Clostridium difficile — “C. diff” — the most common cause of hospital-acquired infections.
By Leigh MacMillan
November 4, 2015

Detect and defend against pathogens

Understanding factors, such as the receptor TLR9, that detect and defend against pathogens may lead to therapeutic approaches that promote an effective immune response to treat infections.
By Leigh MacMillan
1 2 3 4 5