Dysfunction of the endothelial cells that line blood vessels may contribute to delirium and coma in critically ill patients – and could be a target for therapy.
Targeting repair pathways in the lung’s air sacs may be a valuable therapeutic direction for pulmonary fibrosis – the scarring of lung tissue.
Overexpression of a gene that is a common culprit in leukemia induces stem cell-like features in T cells, which may enable the cells to become cancerous.
Nobel laureate Lee Hartwell, Ph.D., will deliver the next Flexner Discovery Lecture on Thursday, April 11.
Immune cells that recognize self antigens (e.g. insulin), but are functionally silent, can trigger autoimmune diseases such as diabetes.
The gene Has2 participates in signaling that is important in developing fingers and toes, and may have relevance for cancer development.
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