Leigh MacMillan

April 25, 2014

Increased cell permeability may protect from colitis

Having a “leaky” gut may protect against colitis, a paradoxical finding that alters understanding of the role of cell permeability in intestinal homeostasis and immune regulation.

By Leigh MacMillan
April 24, 2014

New view of neurotransmitter transport

Dynamic measurements of the bacterial leucine transporter shed light on the transporters that play roles in neuropsychiatric and addiction disorders.

By Leigh MacMillan
April 17, 2014

Nutrient-absorbing surface’s assembly revealed: study

Vanderbilt University researchers have discovered how intestinal cells build the “brush border” — a specialized surface structure that is critical for absorbing nutrients and defending against pathogens.

By Leigh MacMillan
April 15, 2014

Anthrax bacteria’s signaling systems

Vanderbilt researchers have identified a new signaling system that anthrax bacteria uses to infect its host.

By Leigh MacMillan
April 11, 2014

Myelin junctions key to conduction

A protein in the myelin coating on nerves helps form a “seal” that enables effective nerve conduction; loss of the protein causes inherited neuropathies.

By Leigh MacMillan
March 31, 2014

E-records shed light on drug response

Electronic medical records linked to DNA biobanks are a valid resource for defining and understanding the genetic factors that contribute to drug response.

By Leigh MacMillan
March 28, 2014

Mapping brain circuitry

Vanderbilt investigators have used two types of neuroimaging to establish a “map” of connections for a brain region important in anxiety and addiction.
By Leigh MacMillan
March 27, 2014

Cell signaling expert Clapham set for next Discovery Lecture

Neuroscientist and biophysicist David Clapham, M.D., Ph.D., known for his studies of ion channels and cell signaling, will deliver the next Flexner Discovery Lecture on Thursday, April 3, in 208 Light Hall.
By Leigh MacMillan
March 27, 2014

Study links stem cell gene to prostate cancer susceptibility

A gene on chromosome 8 — in a region of the genome linked to risk for many types of cancer — is particularly associated with prostate cancer susceptibility, Vanderbilt University researchers have found.
By Leigh MacMillan
March 17, 2014

Delirium increases long-term disability

Patients who suffer a longer duration of delirium in the intensive care unit are more likely to experience long-term disability after discharge.
By Leigh MacMillan
March 14, 2014

Protein boosts retinal neuron survival

An ion channel protein called TRIPV1 helps retinal neurons survive the elevated eye pressure associated with glaucoma.
By Leigh MacMillan
March 13, 2014

A new way to target cancer-driver Ras

Vanderbilt researchers have discovered small molecules that turn off cancerous Ras signals in a new way.
By Leigh MacMillan
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