Leigh MacMillan Archive — Page 62 of 85

Heart illustration thumbnail
December 18, 2014

Atrial disease and hypertension links

New findings suggest that misfolded proteins accumulate in the heart atria, particularly in patients with hypertension, and may contribute to atrial heart disease.

Illustration of red blood cells flowing through a narrowed blood vessel partially blocked by a yellow fatty plaque.
December 17, 2014

Target for atherosclerosis therapies

A newly identified “atheroprotective” gene is a tool for exploring plaque pathophysiology and may be a good target for therapies to slow atherosclerosis progression.

December 16, 2014

Retinal neuron survival in glaucoma

Understanding how the protein TRPV1 helps neurons survive after glaucoma-related stressors could lead to new therapeutic strategies for glaucoma and other neurodegenerative conditions.

December 11, 2014

Bacterial secretion machinery: 3-D view

New structural findings reveal how “gatekeeper” proteins participate in the secretion systems bacteria use to infect host cells.

Smiling man in a blue sweater and red-striped tie standing in a bright indoor setting.
December 4, 2014

Physician-scientist is dream job for Vanderbilt’s Cassat

Jim Cassat, M.D., Ph.D., a pediatric infectious disease specialist who joined the Vanderbilt faculty this summer, loves taking care of children with bone infections and doing research to understand the host-pathogen interactions during these invasive infections.

November 26, 2014

New tools to probe manganese biology

Vanderbilt researchers have developed tools to probe the role of the essential metal manganese in neurons, and which offer a started point for developing therapeutic agents for manganese-related neurological disorders.