Overexpression of a gene that is a common culprit in leukemia induces stem cell-like features in T cells, which may enable the cells to become cancerous.

Nobel laureate Lee Hartwell, Ph.D., will deliver the next Flexner Discovery Lecture on Thursday, April 11.

Immune cells that recognize self antigens (e.g. insulin), but are functionally silent, can trigger autoimmune diseases such as diabetes.

The gene Has2 participates in signaling that is important in developing fingers and toes, and may have relevance for cancer development.

Berberine, an herbal remedy for diarrhea and intestinal parasites, may be useful in colon cancer therapy.

Sir Rory Collins, MB BS, professor of Medicine and Epidemiology at the University of Oxford, England, will deliver the next Flexner Discovery Lecture on Thursday, April 4.