A team led by Vanderbilt University investigators has discovered two new genes — both coding for the signaling protein calmodulin — associated with severe early-onset disorders of heart rhythm.

The HIF oxygen-sensing pathway and its responses to low oxygen may be targeted for treatments of anemia and disorders of iron balance.

The protein TIP-1 appears to be a novel prognostic marker for glioblastoma and may be a good therapeutic target for disrupting tumor-driven blood vessel development.

An unexpected group of cells generates the coronary arteries and may be useful for regeneration therapies following injury to the heart.

In a wide-ranging lecture that moved from plants to nematode worms to human leukemia, Nobel laureate Andrew Fire, Ph.D., outlined his vision for a genomics-based understanding of how organisms respond to novel information.

The kidney can mediate its own repair through proliferation of resident immune system cells.