Immune cells that recognize self antigens (e.g. insulin), but are functionally silent, can trigger autoimmune diseases such as diabetes.

The gene Has2 participates in signaling that is important in developing fingers and toes, and may have relevance for cancer development.

Berberine, an herbal remedy for diarrhea and intestinal parasites, may be useful in colon cancer therapy.

Sir Rory Collins, MB BS, professor of Medicine and Epidemiology at the University of Oxford, England, will deliver the next Flexner Discovery Lecture on Thursday, April 4.

In critically ill patients with sepsis, plasma hemoglobin may be a new indicator of disease severity – and a potential target for treatment with acetaminophen.

A novel class of drugs that target “BET” proteins may have broad utility for treating genetically diverse brain tumors.