Leigh MacMillan

July 17, 2012

Insights for neuroscience drug discovery

When discovering drugs for brain disorders, it’s important to test the candidates in multiple ways to avoid advancing those with restricted physiological effects.

By Leigh MacMillan
July 3, 2012

Receptor’s role in nutrition brain circuitry

New findings point to brain circuitry that communicates about the body’s nutritional status and regulates how nutrients are mobilized.

By Leigh MacMillan
June 28, 2012

Low oxygen could protect sick kidneys

Low oxygen – and the activation of factors that respond to this situation – may be protective in chronic kidney disease.

By Leigh MacMillan
brain illustration
June 14, 2012

Roots of childhood brain tumors

Cells in the back of the developing brain can give rise to brain tumors, suggesting they may be a target for treatment.

By Leigh MacMillan
June 12, 2012

Making order out of ordinal data

A new statistical tool developed by Vanderbilt biostatisticians will help medical researchers make sense of a commonly encountered – but hard-to-analyze – type of data.

By Leigh MacMillan
June 8, 2012

DNA: From modification to mutation

Understanding how an environmental hazard damages DNA may shed light on processes of tumor formation.

By Leigh MacMillan
May 17, 2012

Long live the therapeutic stem cells

Enhancing stem cell survival is key to improving cell-based therapies for regenerative medicine, and a new drug could help.
By Leigh MacMillan
May 14, 2012

Intestinal artillery launches anti-bacterial attack

The epithelial cells that line the intestines have a newly discovered mechanism for protecting us against microbes: they fire anti-bacterial "bullets" into the gut.
By Leigh MacMillan
May 10, 2012

Probing epilepsy’s molecular sparks

Understanding how mutations in neuronal receptors contribute to epilepsy could lead to improved therapies.
By Leigh MacMillan
April 30, 2012

Better blood pressure-reducing drugs?

A newer version of an old class of blood pressure lowering drugs may offer advantages for obese patients with metabolic syndrome.
By Leigh MacMillan
April 20, 2012

Neuronal clues to cholesterol-defect disorder

Antioxidants may be a beneficial treatment for an inherited genetic disorder.
By Leigh MacMillan
April 17, 2012

Pathways to delirium in the ICU

Study suggests that the “kynurenine” biochemical pathway could be a target for reducing delirium and coma in critically ill patients.
By Leigh MacMillan
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