Leigh MacMillan

Pumping up the pancreas in pregnancy

A strain of mutant mice provide a novel model for studying glucose intolerance and gestational diabetes during pregnancy and suggest that certain molecules may be useful for therapeutic applications.

Fishing for heart attack repair tools

Images of individuals with Alagille syndrome (National Institutes of Health)

Clues to flattened faces

fish skeleton

Clues to skeletal form in ‘feelgood’ fish

Ela Knapik, associate professor of medicine, and colleagues are using zebrafish to explore the molecular and cellular mechanisms that cause birth defects of the face and skeleton.

Move out, cholesterol

Compounds developed at Vanderbilt could offer a whole new way to treat atherosclerosis.

Skeletal defects in genetic disorder

A new mouse model provides a tool for testing novel therapeutic approaches for neurofibromatosis.

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