Aliquots - Research Briefs

October 31, 2019

Imaging host-pathogen battle for metal

An unprecedented view of bacterial products within infected tissues opens new opportunities to explore infection biology and devise novel therapeutic strategies.

By Leigh MacMillan
African American woman in pink crossing her hands over her breast
October 22, 2019

Another way to detect lymphedema

Early detection of lymphedema, which occurs in 20% of patients following breast cancer treatment, may improve therapeutic options for patients.

By Sanjay Mishra
October 21, 2019

Completing DNA synthesis

James Dewar and colleagues have identified a role for the enzyme topoisomerase II in reducing replication errors during the final stage of DNA synthesis.

By Leigh MacMillan
October 17, 2019

Microscopic spines connect worm neurons

Worm neurons have microscopic “spines” — where nerve-to-nerve communication happens — that share features with mammalian neurons, supporting the use of worms to study spine genetics and biology.

By Leigh MacMillan
October 17, 2019

Less inflammation = better healing

Immune cells that produce an anti-inflammatory factor are enriched in fat tissue around the heart and may be good targets to improve heart attack outcomes.

By Bill Snyder
3d rendering white blood cells with red blood cells
October 8, 2019

A new regulator of B cell development

New findings establish a role for the pro-inflammatory molecule IL-33 in the early development of antibody-producing B cells.

By Leigh MacMillan
October 7, 2019

AI maps routes to heart disease

Machine learning on unlabeled electronic health record data has shed light on the emergence of cardiovascular disease.
By Paul Govern
October 3, 2019

A step toward gastric cancer

New research findings provide insight into the detrimental events that develop in response to H. pylori infection.
By Sanjay Mishra
October 3, 2019

A catalog of DNA replication proteins

Vanderbilt scientists have identified 593 proteins that are enriched at sites of DNA duplication and chromatin packaging of newly synthesized DNA.
By Leigh MacMillan
September 24, 2019

Treating C. diff: new purpose for an old drug?

An inexpensive generic drug once used to prevent gastrointestinal ulcers in people taking daily NSAIDs protects against C. diff infection in mice.
By Paul Govern
September 23, 2019

Tailoring treatment for heart defect

By defining the clinical and genetic factors that predict treatment response, Vanderbilt investigators aim to personalize therapy for a common heart complication in preterm infants.
By Leigh MacMillan
September 19, 2019

Microvilli in motion

Live cell imaging studies have revealed that microvilli — finger-like protrusions on the surface of epithelial cells — move and collide as they form the brush border.
By Anivarya Kumar
September 19, 2019

Potential prostate cancer biomarkers

An analysis of more than 140,000 people of European ancestry has identified blood protein biomarkers associated with prostate cancer risk.
By Leigh MacMillan