Aliquots - Research Briefs

April 12, 2013

Lung damage protector

Targeting repair pathways in the lung’s air sacs may be a valuable therapeutic direction for pulmonary fibrosis – the scarring of lung tissue.

By Leigh MacMillan
April 11, 2013

Leukemia culprit’s cellular actions

Overexpression of a gene that is a common culprit in leukemia induces stem cell-like features in T cells, which may enable the cells to become cancerous.

By Leigh MacMillan
April 3, 2013

“Silent” B cells trigger autoimmunity

Immune cells that recognize self antigens (e.g. insulin), but are functionally silent, can trigger autoimmune diseases such as diabetes.

By Leigh MacMillan
April 1, 2013

Fingers and toes: joint forming factor

The gene Has2 participates in signaling that is important in developing fingers and toes, and may have relevance for cancer development.

By Leigh MacMillan
March 29, 2013

Plant compound stops colon cancer cells

Berberine, an herbal remedy for diarrhea and intestinal parasites, may be useful in colon cancer therapy.

By Leigh MacMillan
March 28, 2013

Acetaminophen: protective in sepsis?

In critically ill patients with sepsis, plasma hemoglobin may be a new indicator of disease severity – and a potential target for treatment with acetaminophen.

By Leigh MacMillan
March 20, 2013

New drugs a good BET for brain cancer

A novel class of drugs that target “BET” proteins may have broad utility for treating genetically diverse brain tumors.
By Leigh MacMillan
March 18, 2013

IRF6 on the tip of tongue development

The factor IRF6 plays important roles in the development of the tongue.
By Leigh MacMillan
March 15, 2013

Diagnostic codes identify smoking status

Diagnostic codes used for billing purposes effectively identify smokers in a general clinic population and can be used to adjust smoking status in genetic and epidemiologic studies.
By Leigh MacMillan
March 14, 2013

Bacterial resistance breaks bridges

Understanding how bacteria become resistant to quinolone antibiotics could guide strategies for developing new antibacterial drugs.
By Leigh MacMillan
March 6, 2013

Tick-tock – predicting menopause

An ultrasound count of potentially egg-producing follicles could predict the timing of menopause.
By Leigh MacMillan
March 4, 2013

Gene ‘dose’ may be key to autism

Individuals with overexpression of the gene MECP2 have core features of autism spectrum disorder.
By Bill Snyder
March 1, 2013

Target for inflammatory bowel disease

The factor STAT6 appears to play a role in the pathogenesis of an inflammatory bowel disease, suggesting it may be a promising target for new treatments.
By Leigh MacMillan
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