Division of Nephrology and Hypertension

The role of integrins in kidney “integrity”

Receptors called integrins play a critical role in maintaining the structure of the kidney, Vanderbilt researchers have discovered.

Osama El Shamy, MD, and Megha Salani, MD, are working to expand VUMC’s Home Dialysis Program.

Home Dialysis Program experiencing rapid growth

Osama El Shamy, MD, assistant professor of Medicine in the Division of Nephrology and Hypertension, has long been a proponent of the benefits of home dialysis.

Gene expression in diabetic nephropathy

Vanderbilt researchers are looking to mRNA populations in podocytes — kidney cells that help filter blood — to help identify potential targets for treating diabetic kidney disease.

Clue to diabetic kidney disease

Vanderbilt researchers have identified a signaling pathway that promotes kidney fibrosis in patients with diabetes — and that could be targeted with an existing approved medication.

William Fissell, MD, has been working on the Kidney Project to create an implantable bioartificial kidney for the last decade.

VUMC, UCSF win KidneyX award for implantable home dialysis system

A $500,000 KidneyX prize has been awarded to The Kidney Project — a collaboration between Vanderbilt University Medical Center and University of California, San Francisco (UCSF) — for the development of an implantable dialysis system that would enable patients to safely and effectively treat kidney failure at home.

Protecting the injured kidney

Leslie Gewin and colleagues have upended conventional dogma about Wnt/beta-catenin signaling in the kidney, finding that it protects against chronic kidney disease rather than promoting it.

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