The rigidity of the extracellular matrix that surrounds cells impacts the contractile and invasive properties of head and neck cancer cells.
The contractile machinery inside tumor cells increases invasive properties, suggesting it might be a good target to inhibit cancer cell spread.
Vanderbilt investigators have identified how two key components of cancer’s invasive “switch” — the series of signaling events that turn on a tumor cell’s invasive behavior — work together.
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