NIH

Food variety drives overeating in mouse model of obesity syndrome

Dietary variety – not high-fat or sugary foods – appears to stimulate overeating in a mouse model of an inherited obesity syndrome.

‘Longevity’ gene aids kidney survival

A gene associated with cell survival and longevity may protect the kidney from acute injury.

A role for blood vessels in delirium?

Dysfunction of the endothelial cells that line blood vessels may contribute to delirium and coma in critically ill patients – and could be a target for therapy.

Lung damage protector

Targeting repair pathways in the lung’s air sacs may be a valuable therapeutic direction for pulmonary fibrosis – the scarring of lung tissue.

Leukemia culprit’s cellular actions

Overexpression of a gene that is a common culprit in leukemia induces stem cell-like features in T cells, which may enable the cells to become cancerous.

“Silent” B cells trigger autoimmunity

Immune cells that recognize self antigens (e.g. insulin), but are functionally silent, can trigger autoimmune diseases such as diabetes.

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