NIH

VU study finds stress fuels breast cancer metastasis to bone

Stress can promote breast cancer cell colonization of bone, Vanderbilt Center for Bone Biology investigators have discovered.

Insights for neuroscience drug discovery

When discovering drugs for brain disorders, it’s important to test the candidates in multiple ways to avoid advancing those with restricted physiological effects.

Gene’s impact on ‘good’ cholesterol could affect heart disease risk

A genetic variant may help keep an individual’s “good” cholesterol in check.

Receptor’s role in nutrition brain circuitry

New findings point to brain circuitry that communicates about the body’s nutritional status and regulates how nutrients are mobilized.

Low oxygen could protect sick kidneys

Low oxygen – and the activation of factors that respond to this situation – may be protective in chronic kidney disease.

Neurons with serotonin transporters labeled with quantum dots. (Jerry Chang / Vanderbilt)

Probing the roots of depression by tracking serotonin regulation at a new level

An interdisciplinary team of scientists have successfully tagged a protein that regulates the neurotransmitter serotonin with tiny fluorescent beads, allowing them to track the movements of individual molecules for the first time. This capability makes it possible to study the manner in which serotonin regulates mood, appetite and sleep at a new level of detail.

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