Proceedings of the National Academy of Sciences

April 14, 2017

A new mode of DNA repair

Structural details of a protein that removes DNA lesions shed light on fundamental mechanisms of DNA repair.

By Leigh MacMillan
February 2, 2017

New target for chronic infection

An enzyme in macrophage immune cells may be a good target for treating chronic infections, Vanderbilt researchers have discovered.

By VUMC News and Communications
knight with sword and shield
October 20, 2016

Research sheds light on how RSV wards off potential vaccines

Respiratory syncytial virus (RSV) is the major cause of life-threatening viral pneumonia in infants worldwide, yet despite repeated efforts, scientists have been unable to develop an effective vaccine against it.

By Bill Snyder
September 28, 2016

Targeting norovirus “noxiousness”

New discoveries will guide efforts to develop vaccines or antiviral agents for norovirus, the most common cause of infectious diarrhea.

By Bill Snyder
June 2, 2016

VUMC researchers seek to crack the code of neonatal sepsis

Sepsis, an exaggerated and overwhelming inflammatory response to infection, is a major worldwide killer of babies in the first four weeks of life (neonatal period).

By Bill Snyder
May 13, 2016

New pain medicine from a fungus?

Collybolide – a natural product isolated from a mushroom – is a promising candidate for the development of non-addictive pain medicines.

By Sanjay Mishra
April 29, 2016

Improving natural killer cancer therapy

A newly discovered mechanism that helps cancer cells avoid destruction by immune system cells may improve immunotherapies.
By Sanjay Mishra
March 8, 2016

Fat hormone’s role in zebrafish

The hormone leptin regulates glucose balance, but not fat stores, in zebrafish.
By Leigh MacMillan
February 11, 2016

Slight chemical change may improve TB treatments: study

One small chemical change to an existing antibacterial drug results in a compound that is more effective against its target enzyme in tuberculosis, Vanderbilt researchers have discovered.
By Leigh MacMillan
February 5, 2016

Dynamics of a drug resistance transporter

Vanderbilt investigators are exploring the shape changes in a multidrug transporter to understand the mechanisms of antibacterial resistance.
By VUMC News and Communications
January 8, 2016

Copying chromosome caps

Telomeres – the caps on the end of chromosomes – are a source of stress for a particular protein involved in copying DNA, a new study reports.
By Leigh MacMillan
October 29, 2015

Compound developed at VUMC may delay Huntington’s disease

A compound developed by researchers at Vanderbilt University can improve early symptoms and delay progression of Huntington’s disease in a mouse model of the neurodegenerative disorder.
By Bill Snyder
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