asthma

November 13, 2024

Study to explore antibiotics’ role in childhood asthma

Goal is to inform the design of microbiome-based therapeutics that can help deliver antibiotics safely during early life and reduce the burden of childhood asthma.

By Jessica Pasley
October 25, 2024

Asthma drug does not speed COVID-19 recovery: study

The study, a randomized and controlled clinical trial, tested the effectiveness of montelukast in 1,250 outpatients with acute post-COVID-19 symptoms.

By Bill Snyder and Shantell Kirkendoll
Image of the U.S., with markers that note cities where the Home Owners’ Loan Corp. conducted a city survey of impacted areas. (Source: Mapping Inequality)
September 24, 2024

Poverty rates linked to asthma in ‘redlined’ areas

Neighborhoods that were discriminated against, called ‘redlined areas,’ are known to have higher levels of air pollution from industry and vehicles, especially diesel-fueled trucks, buses and cars.

By Craig Boerner
A clinical trial supports approval of a new medication to treat moderate-to-severe asthma in children.
April 24, 2023

Study finds early RSV infection linked to significantly increased risk of asthma in children

A Vanderbilt study has found that RSV infection in the first year of life is associated with a significantly increased risk of asthma in children.

By Nancy Humphrey
February 21, 2023

Diabetes drug may improve asthma

New biomarker finding strengthens the case for using GLP-1R agonists to treat patients with Type 2 diabetes who also suffer from asthma.

By Sarah E. Glass
The clinical trial group includes, from left, Gordon Bernard, MD, Katherine Cahill, MD, Kevin Niswender, MD, PhD, Pingsheng Wu, PhD, and R. Stokes Peebles, MD.
November 10, 2022

Clinical trial at VUMC tests novel treatment for asthma

VUMC has begun enrolling patients with asthma in a clinical trial of a novel treatment: a medication approved to treat diabetes and obesity.

By Leigh MacMillan
July 21, 2022

Study explores role RSV plays in later asthma development

A Vanderbilt clinical project will follow 1,950 Middle Tennessee children to determine how genes and the environment interact with RSV infection during the first year of life and contribute to asthma development
By Leah Mann
December 8, 2021

International study supports dupilumab for treatment of moderate-to-severe asthma in children

In a late-stage clinical trial, the biologic agent dupilumab reduced the rate of severe asthma attacks and improved lung function and asthma control for children ages 6 to 11 with moderate-to-severe asthma, offering a new option to these patients.
By Leigh MacMillan
November 11, 2021

CRISPR screen identifies new anti-inflammatory drug target

A novel CRISPR screen developed by Vanderbilt researchers identified a promising new target for anti-inflammatory therapeutics.
By Leigh MacMillan
May 20, 2021

Type 2 diabetes medication shown to benefit asthma patients

Type 2 diabetes patients who also have asthma are benefitting from a diabetes medication, typically given to help the pancreas produce more insulin, that also improves asthma symptoms and may reduce lung and airway inflammation.
By Craig Boerner
March 25, 2021

Team studies new use for pulmonary hypertension drug

An FDA-approved medication enhances the function of T regulatory cells (Treg), a class of immune cells that restrains the immune response, Vanderbilt investigators have discovered.
By Leigh MacMillan
October 1, 2019

Pua lands NIH Director’s New Innovator Award

Heather Pua, MD, PhD, one of 60 investigators to receive the 2019 NIH Director’s New Innovator Award, will explore a novel type of cell signaling by RNAs in allergic airway inflammation.
By Leigh MacMillan
January 31, 2019

Destructive ‘telegrams’ in asthma

Vanderbilt investigators have discovered that certain microRNAs — "telegram"-like signals — increase after the induction of allergic airway inflammation.
By Bill Snyder
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