Department of Pathology Microbiology and Immunology

Zinc deficiency promotes Acinetobacter lung infection: study

The study findings point to the potential of interleukin-13 antibodies — approved for use in humans — as a treatment to protect against bacterial pneumonia in patients with zinc deficiency.

James Crowe Jr. honored for his innovative research on human antibodies

Crowe and his colleagues have developed cutting-edge technologies to isolate and study antiviral antibodies.

VUMC method tracks down rare, broadly reacting antibodies: study

The discovery, reported in the journal PLOS Pathogens, could help open the door to the development of effective vaccines and antibody therapies with an “exceptional breadth of pathogen coverage.”

Fever drives enhanced activity, mitochondrial damage in immune cells

The mechanistic understanding of how cells respond to heat could explain how chronic inflammation contributes to the development of cancer.

Bacterial metabolism plays role in staph antibiotic tolerance

Staph is a leading bacterial cause of death from bloodstream, bone and joint infections, in part because of high rates of antibiotic treatment failure.

Rare diseases point to connections between metabolism and immunity

Science Immunology study suggests a new class of inborn errors of immunometabolism and could improve care for patients with these complex diseases.

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