diabetes

Insulin in vials
June 12, 2014

Study tracks insulin’s risks as second-line diabetes medication

In an observational study by researchers at Vanderbilt University Medical Center, adults with type 2 diabetes who take insulin in addition to the recommended first-line drug therapy, metformin, had a 30 percent higher risk of heart attack, stroke or death when compared to similar patients who instead augment their metformin regimen with a sulfonylurea.

By Paul Govern
Insulin in vials
May 14, 2014

CaMKII enhances insulin secretion

The protein CaMKII acts as a calcium sensor in a positive feedback pathway that enhances glucose-stimulated insulin secretion.

By VUMC News and Communications
Insulin in vials
April 10, 2014

Matrix remodeling and insulin resistance

The extracellular matrix that surrounds cells plays a role in the development of insulin resistance.

By Will Fry
March 20, 2014

Diabetes study offers medication adherence options

Knowing when to take a medication — and what to do if a dose is missed — could greatly improve adherence to diabetes medications and glycemic control among adults with type 2 diabetes, according to a Vanderbilt study published in the journal Diabetes Care.

By Craig Boerner
March 13, 2014

Diabetes researchers track cells’ ability to regenerate

Vanderbilt University scientists have found evidence that the insulin-secreting beta cells of the pancreas, which are either killed or become dysfunctional in the two main forms of diabetes, have the capacity to regenerate.

By Bill Snyder
cells
January 13, 2014

Searching for beta cell stimulators

Vanderbilt researchers describe a new technique for identifying factors that stimulate the proliferation of pancreatic beta cells – factors that might offer therapeutic options for diabetes.

By Leigh MacMillan
January 8, 2014

Young children engage in physical activity in short spurts; preschoolers take 11 hours to attain daily exercise levels

Preschool-aged children require the majority of their waking day to achieve their recommended daily physical activity, a Vanderbilt study published in Obesity found.
By VUMC News and Communications
December 19, 2013

Bariatric surgery’s metabolic impact to be explored

Vanderbilt University researchers have received a two-year, $1.2 million grant from the National Institutes of Health (NIH) to study a mouse model of the metabolic and hormonal changes caused by bariatric surgery.
By VUMC News and Communications
December 5, 2013

Day of events highlights efforts to fight diabetes

Vanderbilt University’s contributions to the field of diabetes — past and present — were celebrated recently during the annual Diabetes Day at the Vanderbilt Student Life Center.
By Bill Snyder
November 14, 2013

Diabetes Center to celebrate major milestones

The Vanderbilt Diabetes Center is celebrating two significant milestones this month.
By Bill Snyder
October 24, 2013

Glucose control study gives patients new path to health

The IDIOM study is designed to compare how a diet with moderate caloric restriction, alone or with long-acting insulin, affects areas of the brain’s dopamine system that are involved in food intake, reward and the sense of pleasure people get from eating.
By Jessica Pasley
October 24, 2013

Study sheds new light on type 2 diabetes development

Inactivation by oxidative stress of specific transcription factors essential for pancreatic islet beta cell function is a key event in the development of type 2 diabetes, Vanderbilt University researchers and their colleagues have found.
By Bill Snyder
October 16, 2013

Relaxin combats insulin resistance

The hormone relaxin may offer a novel approach for treating diet-induced insulin resistance.
By Leigh MacMillan
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