James Sutcliffe

A rise in a mother’s blood levels of serotonin — a neurotransmitter that regulates mood, memory and gastrointestinal function — is associated with some, but not all forms of autism in children. (illustration by Diana Duren with Adobe Stock)

Study sheds new light on autism, but there’s more work to be done

A target of their investigations is serotonin, a signaling molecule that is well known for its critical roles in regulating mood and which also plays an important role in the development of the brain and nervous system.

autism concept: puzzle

Study may point to new treatment approach for ASD

Using sophisticated genome mining and gene manipulation techniques, researchers at Vanderbilt University Medical Center (VUMC) have solved a mystery that could lead to a new treatment approach for autism spectrum disorder (ASD).

puzzel pieces, autism

Altered dopamine signaling may offer a clue to autism

Newly discovered genetic variations linked to autism spectrum disorder (ASD) disrupt the function of the dopamine transporter, suggesting that altered dopamine signaling contributes to this common developmental condition, according to a Vanderbilt University-led research team.

Transporter linked to autism risk

Vanderbilt University investigators for the first time have linked a non-inherited, de novo mutation in the dopamine transporter to autism spectrum disorder (ASD).

Vanderbilt Center for Human Genetics Research investigators join international team of experts to find genetic links to autism; Results published in Nature Genetics

A team of Vanderbilt Center for Human Genetics Research investigators and colleagues from around the world are releasing findings from the largest study to date seeking to identify genes that might increase the risk of autism.