Scientific Reports (journal)

September 14, 2017

Acid reflux cancer link

Blocking acid reflux-induced production of reactive oxygen compounds may be a useful strategy for preventing DNA damage and decreasing the risk of esophageal cancer.

By Sanjay Mishra
March 16, 2017

Esophageal cancer complexities

New findings that reveal complex interactions in esophageal adenocarcinoma could lead to diagnostic, prognostic or therapeutic biomarkers.

By VUMC News and Communications
March 9, 2017

Melanoma study finds new way to enhance targeted therapies

With the help of a drug formerly used to treat HIV/AIDS, researchers at Vanderbilt University Medical Center (VUMC) have found a way to make melanoma cells more vulnerable to targeted anti-cancer therapy.

By Bill Snyder
January 20, 2017

Improving vaccine formulations

The compound MPLA is an attractive vaccine component, designed to elicit a robust immune response.

By Sanjay Mishra
December 1, 2016

Investigators explore new way to control mosquitoes

In a new study, Vanderbilt pharmacologist Jerod Denton, Ph.D., Ohio State entomologist Peter Piermarini, Ph.D., and colleagues report an experimental molecule that inhibits kidney function in mosquitoes and thus might provide a new way to control the deadliest animal on Earth.

By Paul Govern
brain and lightning
November 10, 2016

Protein structure and epilepsy severity

Understanding how mutations affect the structure and function of inhibitory neurotransmitter receptors will shed light on the mechanisms underlying some types of epilepsy.

By VUMC News and Communications
June 6, 2016

Pulmonary fibrosis culprits

New findings identify isoketal-modified proteins as a previously unrecognized feature of pulmonary fibrosis and as a potential therapeutic target for this disease.
By Leigh MacMillan
January 21, 2016

New targets for diabetic retinopathy

Certain protein factors have been identified as attractive targets for treating diabetic retinopathy, a major cause of blindness in adults.
By VUMC News and Communications
February 19, 2015

‘Stretched’ cells promote cancer

Mechanical stress appears to be a critical factor in activating normal tissue-associated fibroblasts to generate cancer-associated fibroblasts.
By Leigh MacMillan
November 26, 2014

New tools to probe manganese biology

Vanderbilt researchers have developed tools to probe the role of the essential metal manganese in neurons, and which offer a started point for developing therapeutic agents for manganese-related neurological disorders.
By Leigh MacMillan