sepsis

storming night with many bolts of lightning

VU scientists report a way to calm the sepsis “storm”

Researchers at Vanderbilt University Medical Center (VUMC) have found a way to calm the “genomic storm” that triggers the often-lethal consequences of sepsis.

Pathology of septic shock

The signaling molecule IL-15 promotes septic shock, a life-threatening condition involving organ injury caused by infection.

VUMC researchers seek to crack the code of neonatal sepsis

Sepsis, an exaggerated and overwhelming inflammatory response to infection, is a major worldwide killer of babies in the first four weeks of life (neonatal period).

blood cells

Immune tolerance in endothelial cells

Inducing “tolerance” to bacterial toxins in the endothelial cells that line blood vessels may offer a new approach for preventing the negative consequences of sepsis.

Antibiotics, fetal vessel defect linked

Certain antibiotics increase the risk of a congenital heart disorder called patency of the ductus arteriosis.

Acetaminophen: protective in sepsis?

In critically ill patients with sepsis, plasma hemoglobin may be a new indicator of disease severity – and a potential target for treatment with acetaminophen.

1 2