Vanderbilt Memory and Alzheimer’s Center

September 3, 2020

New clue to Alzheimer’s disease

Combining studies of genetically diverse mouse populations and human data led to the identification of a gene associated with cognitive decline and brain changes in Alzheimer’s disease.

By Bill Snyder
August 6, 2020

Grant supports research on abnormal brain aging

With the aid of an $18.2 million, five-year grant renewal from the National Institute on Aging, the Vanderbilt Memory and Aging Project (VMAP) will advance interdisciplinary research into abnormal brain aging and cognitive decline in older adults, with continuing emphasis on the role of blood flow changes in the heart and brain.

By Paul Govern
May 7, 2020

New study examines Alzheimer’s disease images and molecular biomarkers

Alzheimer’s disease (AD) involves distinctive wasting away of certain brain regions, such that medical imaging of these regions can distinguish the disease from other subtypes of dementia.

By Paul Govern
October 17, 2019

Grant bolsters Schrag’s Alzheimer’s disease research

Matthew Schrag, MD, PhD, assistant professor of Neurology, has received a Paul B. Beeson Emerging Leaders Career Development Award in Aging for research into the function of a novel protein linked to Alzheimer’s disease risk.

By Holly Fletcher
March 21, 2019

Small vessel disease MRI marker linked to worse cognitive health in older adults

Enlarged perivascular spaces, which are commonly seen on brain MRIs in older adults, have important associations with worse cognitive performance, particularly information processing speed and executive function, according to a new study that challenges historical consideration that perivascular spaces are a harmless imaging marker.

By Holly Fletcher
August 30, 2018

Study links aortic stiffness with lower cerebral blood flow

Greater aortic stiffness is related to lower cerebral blood flow, especially among individuals with increased genetic predisposition to Alzheimer’s disease, according to research from Vanderbilt University Medical Center.

By Tom Wilemon
May 7, 2018

Study provides robust evidence of sex differences with Alzheimer’s gene

The APOE gene, the strongest genetic risk factor for Alzheimer’s disease, may play a more prominent role in disease development among women than men, according to new research from the Vanderbilt Memory and Alzheimer’s Center.
By Tom Wilemon
November 8, 2017

Research links heart function to brain’s memory center

Research by a team of Vanderbilt University Medical Center (VUMC) scientists suggests that older people whose hearts pump less blood have blood flow reductions in the temporal lobe regions of the brain, where Alzheimer’s pathology first begins.
By Tom Wilemon
June 2, 2016

Tool sought for doctors to quickly identify patients at risk for cognitive decline

Katherine Gifford, Psy.D., is testing simple questions to see which ones yield the most reliable results as she develops a questionnaire for primary care providers to quickly identify patients at risk for cognitive decline.
By Tom Wilemon
April 28, 2016

Investigators explore African ancestry, Alzheimer’s risk

Higher genomic levels of African ancestry are associated with an increased risk for Alzheimer’s disease, a consortium of investigators reported recently in Alzheimer’s & Dementia.
By Leigh MacMillan
September 10, 2015

Gifford, Bell land development awards in aging research

Two faculty members of the Vanderbilt Memory and Alzheimer’s Center are among a handful of 2015 scholars for the Paul B. Beeson Career Development Awards in Aging Research Program.
By Tom Wilemon
March 3, 2015

Study shows poor heart function could be major Alzheimer’s disease risk

A healthier heart could prevent Alzheimer’s disease, according to new research at Vanderbilt University Medical Center.
By VUMC News and Communications
April 10, 2014

Study explores genetics behind Alzheimer’s resiliency

Autopsies have revealed that some individuals develop the cellular changes indicative of Alzheimer’s disease without ever showing clinical symptoms in their lifetime.
By VUMC News and Communications
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