Research

November 29, 2018

Lung cancer survival signal

A receptor thought to be a cell growth inhibitor actually sends pro-survival signals in small cell lung cancer and is a candidate biomarker for poor prognosis.

By VUMC News and Communications
November 29, 2018

Parsing diabetic skin infections

Vanderbilt researchers have discovered a role for an inflammatory mediator in diabetic skin infections, suggesting new therapeutic targets for this common complication of diabetes.

By Paul Govern
November 15, 2018

Lynn Maquat, PhD, to give Vanderbilt Prize lecture Nov. 29

Lynne Maquat, PhD, recipient of the 2017 Vanderbilt Prize in Biomedical Science whose work has advanced our understanding of human gene expression, will deliver her Vanderbilt Prize lecture as part of the Flexner Discovery Lecture series on Nov. 29.

By Bill Snyder
November 15, 2018

Immunotherapies linked to specific heart complications

In the first large-scale analysis of cardiovascular complications linked to immune checkpoint inhibitors, Vanderbilt researchers have shown that heart and vessel complications include myocarditis, pericarditis, vasculitis and arrhythmias, and that they occur early in the course of treatment.

By Tom Wilemon
Lymphocytes attacking cancer cell
November 8, 2018

Evading cell death

Stress granules that form in response to cellular stress help cancer cells survive and develop resistance to treatment.

By VUMC News and Communications
November 8, 2018

Vitamin C protects brain from seizures

Brain ascorbate — vitamin C — is important for protecting the brain against seizures and cognitive decline in Alzheimer’s disease.

By Nora Foegeding
November 8, 2018

Novel methods to treat glaucoma

Increasing a certain signaling molecule prevents the degeneration of retinal cells that are lost in glaucoma, suggesting a new way to treat this disease.
By VUMC News and Communications
November 8, 2018

Obesity negates beneficial drug effects

A drug that improves levels of “good” cholesterol may not be beneficial for obese individuals, Vanderbilt researchers have discovered.
By VUMC News and Communications
November 1, 2018

Team’s findings show glutamine metabolism affects T cell signaling

The cellular nutrient glutamine launches a metabolic signaling pathway that promotes the function of some immune system T cells and suppresses others, Vanderbilt researchers have discovered.
By Leigh MacMillan
October 26, 2018

Clues to bone metastases

Vanderbilt researchers are developing new approaches to study the mechanisms underlying why breast cancer cells home to bone and lie dormant, evading treatment.
By Sanjay Mishra
October 26, 2018

Fetal membranes and microbial threats

Understanding how cells communicate in the membranes surrounding the developing fetus could suggest new strategies for preventing infections, premature birth and adverse pregnancy outcomes.
By Leigh MacMillan
October 25, 2018

Probing the pathology of impaired cognition

Detecting the neuropathology underlying cognitive impairment by lead to new targeted therapies.
By Bill Snyder
October 25, 2018

Studying cellular deliveries

Vanderbilt researchers have characterized the functional transfer of long RNAs between colorectal cancer cells — a form of cell-cell communication that may contribute to cancer aggressiveness.
By VUMC News and Communications
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