Research

Cholesterol
November 8, 2018

Obesity negates beneficial drug effects

A drug that improves levels of “good” cholesterol may not be beneficial for obese individuals, Vanderbilt researchers have discovered.

By VUMC News and Communications
November 1, 2018

Team’s findings show glutamine metabolism affects T cell signaling

The cellular nutrient glutamine launches a metabolic signaling pathway that promotes the function of some immune system T cells and suppresses others, Vanderbilt researchers have discovered.

By Leigh MacMillan
October 26, 2018

Clues to bone metastases

Vanderbilt researchers are developing new approaches to study the mechanisms underlying why breast cancer cells home to bone and lie dormant, evading treatment.

By Sanjay Mishra
October 26, 2018

Fetal membranes and microbial threats

Understanding how cells communicate in the membranes surrounding the developing fetus could suggest new strategies for preventing infections, premature birth and adverse pregnancy outcomes.

By Leigh MacMillan
October 25, 2018

Probing the pathology of impaired cognition

Detecting the neuropathology underlying cognitive impairment by lead to new targeted therapies.

By Bill Snyder
October 25, 2018

Studying cellular deliveries

Vanderbilt researchers have characterized the functional transfer of long RNAs between colorectal cancer cells — a form of cell-cell communication that may contribute to cancer aggressiveness.

By VUMC News and Communications
October 25, 2018

Rothamel selected as Vanderbilt Prize Student Scholar

Katherine Rothamel, a PhD student in the Department of Biochemistry at Vanderbilt University School of Medicine, has been selected as the 2017 Vanderbilt Prize Student Scholar.
By Bill Snyder
October 25, 2018

Combination therapy improves small-cell lung cancer survival

Patients with stage IV small-cell lung cancer lived longer when given the immunotherapy atezolizumab with chemotherapy, setting the stage for what could become the first new treatment approved in decades for this particularly aggressive form of lung cancer.
By Tom Wilemon
October 22, 2018

Antipsychotics ineffective for treating ICU delirium: study

Critically ill patients are not benefiting from antipsychotic medications that have been used to treat delirium in intensive care units (ICUs) for more than four decades, according to a study released today in the New England Journal of Medicine.
By Craig Boerner
October 18, 2018

MIT’s Amon named to receive Vanderbilt Prize

Angelika Amon, PhD, whose groundbreaking investigations of chromosome segregation during cell division have advanced understanding of how cancer may develop, is the recipient of the 2018 Vanderbilt Prize in Biomedical Science, officials at Vanderbilt University Medical Center (VUMC) announced today.
By Bill Snyder
October 12, 2018

Cellular stress defense

The modular architecture of small heat-shock proteins contributes to the ability of these proteins to aid cells in responding to stress.
By Leigh MacMillan
October 12, 2018

Asthma’s androgen connection

New findings may explain why the prevalence of asthma is higher in women and suggest that testosterone derivatives may be useful for treating more severe types of asthma.
By VUMC News and Communications
October 12, 2018

Targeting diabetic kidney disease

Pathways activated by the epidermal growth factor receptor may be attractive targets to treat diabetic kidney disease, according to new findings from Vanderbilt investigators.
By Sanjay Mishra