Mark Boothby

Glucose metabolism influences B cell function

Glucose metabolism influences the qualities of activated, mature B cells — white blood cells that are required for antibody-mediated immune responses, Vanderbilt researchers discovered.

Low oxygen and antibody responses

Mark Boothby and colleagues are exploring the factors that contribute to antibody production and quality, which are key to our defense against pathogens and response to vaccines.

Disease-fighting antibody production

New research links nutrient-responsive cellular signaling to the antibody-mediated immune response.

Faculty members join March for Science

Among the thousands of scientists and their supporters who participated in Saturday’s March for Science in Nashville and in Washington, D.C., were several faculty members from Vanderbilt University Medical Center and Vanderbilt University.

Oxygen on periodic table

Study explores low oxygen’s impact on antibody quality

Hypoxia (lack of enough oxygen) is bad for the body as a whole, but in the neighborhood where infection-fighting antibodies arise, may be important for keeping proper order.