Aliquots - Research Briefs

WIN for blocking cancer growth

William Tansey and colleagues identified proteins that interact with the cancer drug target WDR5 and are important for cancer cell growth.

doctor checking patient's blood pressure

Mitochondrial stress and hypertension

Oxidative stress and toxic products called isolevuglandins in mitochondria play a role in endothelial dysfunction and hypertension — and getting rid of them with a special “scavenger” molecule has therapeutic potential.

Microbial RNA and rheumatoid arthritis

Small RNAs — short stretches of genetic material — from microbes may be playing a role in rheumatoid arthritis and other autoimmune diseases.

Vitamin D activation and cancer risk

Vitamin D protection against colon cancer varies according to parathyroid hormone response, particularly among women.

Building a cohort, the easy way

An automated system using keyword searches can help identify candidates for clinical trials on adverse drug reactions.

A deeper look at out-of-home care

Geographically targeted efforts to prevent children being placed in out-of-home care might be possible, Vanderbilt researchers report.

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