Aliquots - Research Briefs

February 18, 2021

Genetic clues in eye birth defect

Sabine Fuhrmann and colleagues have discovered a novel underlying cause of coloboma — a birth defect that causes missing tissue in the eye and accounts for up to 10% of childhood blindness.

By Leigh MacMillan
Insulin in vials
February 18, 2021

Gene variant and glucose metabolism

Genetic variation that impacts glucose- and insulin-related signaling affects responses to type 2 diabetes treatments and warrants further study.

By Leigh MacMillan
February 9, 2021

Imaging guidance for nerve repair

A noninvasive, quantitative MRI method could be used after surgical repair of traumatic peripheral nerve injury to help clinicians make decisions about whether additional surgical interventions are needed.

By Leigh MacMillan
HIV cell
February 8, 2021

Key factors in HIV-1 replication

HIV-1, the virus that causes AIDS, exploits inositol phosphates in T cells to aid its own assembly and maturation — suggesting that targeting inositol phosphate binding could inhibit HIV-1 replication.

By Anivarya Kumar
February 4, 2021

New clue to postural tachycardia

Insight into the pathophysiology of an enigmatic and debilitating disease suggests new treatment approaches.

By Bill Snyder
February 4, 2021

Gene network for leukemia factor

A new method speeds the analysis of factors that control gene expression from days to minutes, allowing researchers to uncover new targets for cancer treatment.

By Leigh MacMillan
January 26, 2021

Rare tumor disguised as benign

A rare tumor that causes facial weakness was found masquerading as a more common benign facial tumor.
By Emily Stembridge
January 25, 2021

An interacting factor in leukemia

A blood stem cell protein plays a role in the initiation and progression of leukemia, Vanderbilt researchers have found.
By Anivarya Kumar
January 21, 2021

Inflammation in genetic epilepsy

Brain inflammation links genetic and acquired epilepsy — providing new clues about epilepsy development and pointing to potential treatments.
By Leigh MacMillan
January 21, 2021

WIN for blocking cancer growth

William Tansey and colleagues identified proteins that interact with the cancer drug target WDR5 and are important for cancer cell growth.
By Sarah E. Glass
January 12, 2021

Mitochondrial stress and hypertension

Oxidative stress and toxic products called isolevuglandins in mitochondria play a role in endothelial dysfunction and hypertension — and getting rid of them with a special “scavenger” molecule has therapeutic potential.
By Leigh MacMillan
January 11, 2021

Microbial RNA and rheumatoid arthritis

Small RNAs — short stretches of genetic material — from microbes may be playing a role in rheumatoid arthritis and other autoimmune diseases.
By Leigh MacMillan
January 7, 2021

Vitamin D activation and cancer risk

Vitamin D protection against colon cancer varies according to parathyroid hormone response, particularly among women.
By Paul Govern
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