Aliquots - Research Briefs

October 24, 2014

Immune cells’ role in hypertension

Vanderbilt researchers have discovered that certain immune cells contribute to the development of hypertension, suggesting novel targets for treating the disease.

By Leigh MacMillan
October 23, 2014

New view of transporter dynamics

New insights to the workings of a protein that moves neurotransmitters across the nerve cell membrane could aid the design of more effective antidepressants.

By Bill Snyder
October 15, 2014

Antibiotics, fetal vessel defect linked

Certain antibiotics increase the risk of a congenital heart disorder called patency of the ductus arteriosis.

By VUMC News and Communications
October 14, 2014

Neuronal culprit in genetic disease

A particular neuronal cell population is involved in the pathogenesis of a rare neurological disorder, Vanderbilt researchers have discovered.

By Leigh MacMillan
October 10, 2014

Aspirin and allergies

Drugs such as aspirin and indomethacin may increase sensitivity to airborne allergens by suppressing production of the signaling molecule PGI2, which in turn may offer a new treatment for allergies.

By VUMC News and Communications
October 9, 2014

Long-range signaling to stem cells

The potential for long-range signaling factors – such as those identified in the current study – to regulate stem cell behaviors has implications in tumor progression and metastasis.

By Leigh MacMillan
October 1, 2014

Optical imaging in drug therapy screens

A non-invasive imaging tool could test potential cancer therapies quickly to personalize therapy for patients.
By VUMC News and Communications
September 30, 2014

Seizure mutation impairs receptor

Defects in the production of certain receptors are linked to the pathogenesis of genetic epilepsies and fever-induced seizures.
By Yan Su
September 26, 2014

Biomarker for diabetic eye disease

A person’s mitochondrial gene “signature” could predict risk for diabetic retinopathy and guide early intervention strategies.
By Leigh MacMillan
September 25, 2014

A path to sarcoidosis treatment

Vanderbilt investigators identify a new therapeutic target for the inflammatory lung disease sarcoidosis.
By VUMC News and Communications
September 18, 2014

Dioxin, fathers and preterm birth

Exposure of male mice to the pollutant dioxin causes preterm birth across multiple generations, suggesting that efforts to prevent preterm birth should include pre-conception interventions for dads.
By VUMC News and Communications
September 16, 2014

Patient-derived stem cells shed light on pulmonary hypertension

Stem cells derived from patients with pulmonary arterial hypertension provide a unique resource for studying the molecular defects that cause the disease and testing potential therapies.
By Leigh MacMillan
September 12, 2014

Schizophrenia ‘switches’ discovered

Drugs developed at Vanderbilt could provide a new way to treat schizophrenia in a personalized way.
By Bill Snyder