Health and Medicine

The macrostructure — volume, area and length — of the brain’s white matter is useful for studying aging and could be a sensitive marker for neurodegenerative disorders such as Alzheimer’s disease, Vanderbilt researchers reported.

More than a third of patients presenting at the emergency department with a suspected heart attack have a “delayed” ECG measure of heart function, with Black patients, females and non-English speakers more likely to experience delays.

Using imaging mass spectrometry and microscopy, Vanderbilt researchers visualized how staph bacteria modifies lipids in its membrane to evade immune system-mediated killing.

Targeting receptors of the inflammatory lipid signaling molecule PGE2 may offer a new way to tackle both Type 2 diabetes and cardiovascular disease, Vanderbilt researchers have discovered.

An automated alert to encourage clinicians to coprescribe naloxone for patients at risk of opioid overdose increased naloxone prescriptions per opioid prescription 16-fold.

Including polygenic risk scores for blood pressure may improve predictive models to identify people at risk for treatment-resistant hypertension.

Considering metabolic (CYP2D6) enzyme activity score and patient age may aid in determining an individual’s risk for an adverse event with administration of the anti-arrhythmic drug propafenone.