Research

January 17, 2022

H. pylori, lipid loss and stomach cancer

H. pylori infection — a strong risk factor for stomach cancer — changes the composition of stomach lipids, which could offer new biomarkers for detecting premalignant changes, Vanderbilt researchers discovered.

By Leigh MacMillan
January 14, 2022

Vanderbilt biostatisticians launch Cancer-Immu data portal for predicting response to immune checkpoint blockade immunotherapy

A new data portal called Cancer-Immu established by a team of Vanderbilt University Medical Center biostatisticians can help cancer clinicians and researchers predict which patients will respond to immune checkpoint inhibitors.

By Tom Wilemon
January 13, 2022

The role of integrins in kidney “integrity”

Receptors called integrins play a critical role in maintaining the structure of the kidney, Vanderbilt researchers have discovered.

By Bill Snyder
January 13, 2022

Salmonella overcomes host resistance

The invading pathogen Salmonella, a common cause of food poisoning, can change its metabolism to overcome host resistance to its colonization.

By Leigh MacMillan
January 13, 2022

Study seeks to refine head and neck cancer treatment options

By Bill Snyder
January 6, 2022

Study explores how bacteria become drug resistant

Vanderbilt researchers have revealed more of the inner-workings of a two-stage “molecular motor” in the cell membrane that enables bacteria to become resistant to drugs.

By Bill Snyder
December 24, 2021

Study of fully vaccinated patients with cancer who had breakthrough COVID-19 shows 13% mortality rate

New research finds that fully vaccinated patients with cancer who had breakthrough COVID-19 infections remained at high risk for hospitalization and death.
By Tom Wilemon
December 21, 2021

Study finds apixaban (Eliquis) is preferable to rivaroxaban (Xarelto) for stroke prevention, reduced bleeding complications

By Jill Clendening
December 20, 2021

“Atlas” of lung development may aid efforts to heal premature lungs

Researchers at Vanderbilt University Medical Center have constructed a single-cell “atlas” of lung development that tracks multiple cell types over time.
By Bill Snyder
December 15, 2021

Study finds similar success rates with two devices for breathing tube placement

Two devices for placing a breathing tube during critical illness had similar success rates for intubation on the first attempt, according to a study published Dec. 8 in JAMA.
By Leigh MacMillan
December 14, 2021

Immune landscape in adrenal cancer

The profile of immune-related gene expression and tumor-infiltrating immune cells in adrenocortical cancer suggests targets for new treatment strategies.
By Leigh MacMillan
December 13, 2021

Oral microbes and gastric cancer

Studies in three large population cohorts that include Asian, African American and European American people support a role for the oral microbiota — the collection of microbial species in the mouth — in gastric cancer development.
By Leigh MacMillan
December 10, 2021

“Supermeres” may carry clues to cancer, Alzheimer’s disease and COVID-19

Vanderbilt researchers have discovered a nanoparticle released from cells, called a “supermere,” which contains enzymes, proteins and RNA associated with multiple cancers, cardiovascular disease, Alzheimer’s disease and even COVID-19.
By Bill Snyder