adipose tissue

October 25, 2023

Immune system’s role in metabolic disease detailed in tissue atlas

Researchers at Vanderbilt University Medical Center have published the largest known single-site adipose tissue atlas — a comprehensive, detailed map of the cells, structures and molecules within a specific tissue or organ, designed to support open-ended study.

By Paul Govern
From left, Sheila Collins, PhD, Ryan Ceddia, PhD, and Heidi Hamm, PhD, and their colleagues have identified a potential new approach to reducing the global impact of obesity and diabetes. (photo by Erin O. Smith)
September 6, 2023

Releasing a brake that drives obesity and diabetes

Vanderbilt researchers have uncovered a potential new way to help curb the rapidly rising worldwide prevalence of metabolic disorders, including obesity and diabetes.

By Bill Snyder
January 12, 2023

Study may lead to new diabetes, heart disease treatments

Vanderbilt research found that deletion of an autophagy-participating factor named PIK3C3 from the fat cells of mice led to compromised body temperature control, abnormal blood lipid levels, fatty liver and diabetes.

By Bill Snyder
September 7, 2021

Regulators of fat cell metabolism

Vanderbilt researchers have discovered new details of the regulation of fat cell metabolism, findings that are important for combating obesity.

By Leigh MacMillan
March 18, 2021

HIV, diabetes and immune cells in fat

In HIV-positive individuals with diabetes, immune cells in fat are more proinflammatory and cytotoxic and may represent a therapeutic target for diabetes.

By Leigh MacMillan
December 13, 2018

Lean vs. obese adipose tissue cells

A greater understanding of the mechanisms and cell types involved in returning adipose (fatty) tissue to the lean state may lead to more effective treatments for obesity.

By Bill Snyder