Annals of Neurology

Low-flow cerebrospinal fluid in Huntington’s disease: study

Vanderbilt researchers found reduced net flow of cerebrospinal fluid in Huntington’s disease, which could contribute to mutant protein retention and altered responsiveness to medications delivered via the spinal cord.

photo of David Charles and Mallory Hacker

Deep brain sweet spot might be key to halt Parkinson’s

A sweet spot in the deep brain with direct lines of communication to motor regions far out on the cerebral cortex might hold a key to halting the progression of early-stage Parkinson’s disease.

Myelin junctions key to conduction

A protein in the myelin coating on nerves helps form a “seal” that enables effective nerve conduction; loss of the protein causes inherited neuropathies.