arrestin

Cell fate signaling

A newly identified protein interaction that affects cell cycle regulation may be an attractive target for cancer therapy.

The arrestin-GPCR connection

Understanding details of how arrestins deactivate signaling by G-protein coupled receptors is key to the design of new therapeutics aimed at these cellular “inboxes” that are targeted by up to half of all pharmaceuticals.

Seeing light receptor’s interactions

Understanding how the main receptor for light interacts with other signaling molecules may inform new pharmaceutical development.

Nobel in Chemistry reveals VU ties that bind

Several Vanderbilt researchers have collaborated with this year’s Nobel Chemistry winners.

Clues to retinal cell degeneration

A reversible chemical modification of rhodopsin, a receptor for light, plays a role in the degeneration of retinal cells.