Basic Sciences

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January 17, 2019

Building a pancreas

Vanderbilt investigators are defining the genetic programs that control the development of pancreatic beta cells — studies that could inform new cellular or regenerative therapies for diabetes.

By Leigh MacMillan
December 13, 2018

Lean vs. obese adipose tissue cells

A greater understanding of the mechanisms and cell types involved in returning adipose (fatty) tissue to the lean state may lead to more effective treatments for obesity.

By Bill Snyder
December 13, 2018

Breast cancer-killing RIG

A compound that activates a virus-sensing receptor has potent therapeutic effects in a mouse model of breast cancer.

By Leigh MacMillan
December 13, 2018

The exocyst dynamo

New methods have revealed details of vesicle trafficking in cells and are applicable to any protein complexes, potentially revolutionizing our understanding of cell dynamics.

By Bill Snyder
December 6, 2018

Team seeks to create gene expression map of worm’s nervous system

How do you build a brain? What “rules” govern where neurons end up, how they connect to each other, and which functions they perform?

By Leigh MacMillan
November 29, 2018

Analyzing single-cell landscapes

Vanderbilt researchers have developed a new tool for quantifying data from single-cell studies.

By Leigh MacMillan
November 15, 2018

Four researchers receive Young Investigator Grants

Four Vanderbilt University researchers are among 200 recipients of this year’s Young Investigator Grants awarded by the Brain & Behavior Research Foundation to support “innovative ideas for groundbreaking neurobiological research.”
By Bill Snyder
November 8, 2018

Evading cell death

Stress granules that form in response to cellular stress help cancer cells survive and develop resistance to treatment.
By VUMC News and Communications
November 8, 2018

Novel methods to treat glaucoma

Increasing a certain signaling molecule prevents the degeneration of retinal cells that are lost in glaucoma, suggesting a new way to treat this disease.
By VUMC News and Communications
November 8, 2018

Obesity negates beneficial drug effects

A drug that improves levels of “good” cholesterol may not be beneficial for obese individuals, Vanderbilt researchers have discovered.
By VUMC News and Communications
October 12, 2018

Cellular stress defense

The modular architecture of small heat-shock proteins contributes to the ability of these proteins to aid cells in responding to stress.
By Sanjay Mishra
October 12, 2018

Targeting diabetic kidney disease

Pathways activated by the epidermal growth factor receptor may be attractive targets to treat diabetic kidney disease, according to new findings from Vanderbilt investigators.
By Sanjay Mishra
October 11, 2018

Insulin accelerant

It’s possible to increase the permeability of blood vessels and accelerate insulin action in muscle, Vanderbilt researchers have discovered.
By Laura Daniel
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