New findings suggest that it might be possible to treat diabetes by regenerating insulin-producing beta cells in the pancreas.
The protein CaMKII acts as a calcium sensor in a positive feedback pathway that enhances glucose-stimulated insulin secretion.
Vanderbilt researchers describe a new technique for identifying factors that stimulate the proliferation of pancreatic beta cells – factors that might offer therapeutic options for diabetes.
Adult cells in the pancreas can return to a less mature state – and then become a different cell type, like the beta cells that secrete insulin.
A strain of mutant mice provide a novel model for studying glucose intolerance and gestational diabetes during pregnancy and suggest that certain molecules may be useful for therapeutic applications.
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