blindness

New findings highlight microRNAs — molecules that regulate gene expression — that are differentially expressed in glaucoma and could be candidate biomarkers or targets for therapy.

An imaging probe developed at Vanderbilt detects retinal inflammation early and may allow therapeutic intervention to prevent blindness.

Studies of the molecular complex that helps build specialized cellular surfaces could shed light on the mechanisms underlying a genetic deaf-blindness syndrome accompanied by intestinal disease.

Certain protein factors have been identified as attractive targets for treating diabetic retinopathy, a major cause of blindness in adults.

Vanderbilt investigators demonstrate that a certain eye lens protein is evolutionarily conserved between zebrafish and rat, suggesting that zebrafish can be used as a model system to understand eye lens disorders such as cataracts.

A person’s mitochondrial gene “signature” could predict risk for diabetic retinopathy and guide early intervention strategies.

Understanding the cellular and molecular responses of the eye to blast injury could guide new treatment development.