Bruce Carter

Loss of ‘Jedi’ alters neuron activity

This is not the Jedi you’re thinking of. This Jedi is a receptor that helps clear away dead neurons during development, and its loss changes the activity of dorsal root ganglia neurons, which could have implications for treating chronic pain.

How nerves may lose their insulation

Vanderbilt’s Bruce Carter and colleagues have discovered how genetic changes in the protein PMP22 may contribute to a disease of peripheral nerves.

Enzyme helps build motor that drives neuron death

Vanderbilt scientists have discovered a signaling mechanism that tells neurons to die, findings that could lead to new treatments for neurodegenerative diseases.

Origins of neuroblastoma

Vanderbilt researchers are exploring how neuroblastoma tumors begin and progress, knowledge that could provide new treatments for this pediatric cancer.

Photo: Cunningham Award for Excellence in Biochemistry

How ‘Jedi’ disposes of dead neurons

The protein Syk is essential for clearing away neuron “corpses” in the developing peripheral nervous system.