cancer biology

December 24, 2012

A drug combo for ovarian cancer

Combining another drug with platinum-based chemotherapies may be more effective against ovarian cancer.

By Leigh MacMillan
November 15, 2012

Study tracks antioxidants’ role in prostate tumor growth

Antioxidants promote cell growth in a mouse model of prostate cancer, Vanderbilt researchers report in the journal PLoS ONE. The findings provide insight into the recent controversy regarding antioxidants and prostate cancer prevention.

By Leigh MacMillan
October 23, 2012

Stomach bug alters tumor suppressor

The stomach bug Helicobacter pylori increases forms of a protein that promote tumor development, perhaps explaining how it elevates risk for gastric cancer.

By Leigh MacMillan
October 4, 2012

Proteins help flip tumor’s invasive switch

Vanderbilt investigators have identified how two key components of cancer’s invasive “switch” — the series of signaling events that turn on a tumor cell’s invasive behavior — work together.

By Leigh MacMillan
September 27, 2012

Target acquired for aggressive tumor

New therapeutic target for angiosarcoma – an aggressive, highly fatal tumor of the blood vessels – identified.

By VUMC News and Communications
September 13, 2012

Cells with LIP eat their neighbors

A transcription factor called LIP is capable of causing one cell to consume another.

By Leigh MacMillan
September 11, 2012

Enzyme counters stomach acid attack

Dysfunction or loss of an “antioxidant” enzyme may lead to higher risk for esophageal cancer in patients with gastric reflux disease.
By VUMC News and Communications
August 23, 2012

Gene linked to familial prostate cancer

A rare, inherited mutation confers an eightfold increased risk of prostate cancer, a recent study shows.
By VUMC News and Communications
August 9, 2012

Network approach yields glioblastoma clues

MicroRNA “regulatory networks” generated at Vanderbilt aid search for biomarkers and new drugs to treat glioblastoma, the most common and lethal primary brain tumor.
By Bill Snyder
July 26, 2012

On the hunt for bladder cancer factors

A protein linked to aggressive bladder cancers could point to new strategies for treatment or prevention.
By Leigh MacMillan
July 24, 2012

Proteins guard against cancer spread

Targeting immune system proteins may keep prostate cancer from spreading to bone.
By VUMC News and Communications
July 18, 2012

VU study finds stress fuels breast cancer metastasis to bone

Stress can promote breast cancer cell colonization of bone, Vanderbilt Center for Bone Biology investigators have discovered.
By Leigh MacMillan
April 26, 2012

New drug mutes more melanomas

An experimental melanoma drug may be beneficial for patients not eligible for targeted therapies.
By VUMC News and Communications