cell and developmental biology

Antacids that block a certain enzyme pose a risk for a common cardiac problem in premature infants.

A “profile” of the genes and regulatory networks that govern early heart valve development lay the groundwork for generating valves from a patient’s own cells.

The gene Has2 participates in signaling that is important in developing fingers and toes, and may have relevance for cancer development.

Adult cells in the pancreas can return to a less mature state – and then become a different cell type, like the beta cells that secrete insulin.

An unexpected group of cells generates the coronary arteries and may be useful for regeneration therapies following injury to the heart.

Vanderbilt and University of California investigators have discovered the “cell of origin” for pancreatic ductal adenocarcinoma, a finding that could lead to early detection methods and new treatments.