cell death

The team studying the regulation of innate immune response includes (front row, from left) Yang Zhao, Antiana Richardson, (back row, from left) John Karijolich, PhD, Xiang Ye and William Dunker.
May 6, 2021

Study finds that regulatory protein prevents signaling that triggers cell death

A protein implicated in neurodegenerative diseases including amyotrophic lateral sclerosis prevents the activation of an innate immune response that leads to cell death, Vanderbilt researchers have discovered.

By Leigh MacMillan
red and blue boxing gloves
March 5, 2020

One-two punch for cancer

A drug combination effectively killed aggressive blood cancers in cell and animal models; now it’s being tested in patients.

By Sanjay Mishra
January 31, 2019

Cell death pathway implicated in bone marrow failure

Vanderbilt investigators have linked a specific form of programmed cell death to myelodysplastic syndrome, a type of bone marrow failure.

By Leigh MacMillan
May 8, 2014

PET probe detects dying tumor cells

A novel PET imaging probe detects tumor cell death in vivo and could be useful for personalizing cancer medicine.

By Leigh MacMillan
October 2, 2013

Early cell death in MS

Death of oligodendrocytes, the cells that make myelin, appears to be an early event in the development of multiple sclerosis.

By Leigh MacMillan
August 8, 2013

Nuclear shield against cell death

The protein SARM appears to protect cells from inflammation-driven death by stabilizing the nuclear laminin scaffold.

By Bill Snyder
July 17, 2013

Probing roles of a cell death protein

Vanderbilt researchers have discovered new roles for a protein involved in cell death processes that are activated to prevent tumor-causing DNA mutations.
By Leigh MacMillan
October 25, 2012

Bid protein guards blood cells against stress

A protein normally known to promote cell death found to encourage survival of blood forming cells.
By VUMC News and Communications
September 13, 2012

Cells with LIP eat their neighbors

A transcription factor called LIP is capable of causing one cell to consume another.
By Leigh MacMillan