cell division

March 23, 2023

Decoding cell division machinery

Phosphate modification regulates the cell localization of Cdc15, one of the main controllers of cell division, to fine tune the assembly of cell division machinery.

By Caroline Cencer 
April 16, 2020

‘Tuning’ cell shape for division

Dylan Burnette and colleagues have discovered that two forms of the molecular motor protein myosin have distinct roles in regulating cell shape during cell division.

By Leigh MacMillan
November 18, 2019

Understanding cell division

Vanderbilt researchers have uncovered another piece in the puzzle of how cells divide — a process that goes awry in cancer cells.

By Cayetana Arnaiz Yépez
November 10, 2017

A lipid’s role in cell division

Lipids in the plasma membrane regulate the position of the contractile ring that is required for cell division, Vanderbilt researchers have discovered.

By Natalya Ortolano
November 9, 2017

Advanced imaging tools reveal architecture of cell division machinery

Using super-resolution microscopy tools in the Nikon Center of Excellence, Vanderbilt investigators have determined the molecular architecture of the contractile ring machinery that functions during cell division — a process that is essential for life.

By Leigh MacMillan
June 12, 2017

Repriming replication roadblocks

New findings shed light on how enzymes that replicate DNA skip over mutations that might cause cancer and restart DNA synthesis further away.

By Sanjay Mishra
March 7, 2016

A clue to cell cleavage

Actin and microtubule cytoskeletons are coordinated during cytokinesis – the process that separates one cell into two and is linked to events underlying cancer.
By Sanjay Mishra
January 28, 2016

Findings offer new insight on how cell division proteins work

A family of proteins with critical roles in cell division, synaptic transmission and cell migration don’t all function the way scientists thought they did, according to two new studies led by Vanderbilt researchers.
By Leigh MacMillan
October 30, 2014

VU study reveals factor’s new role in cell division, migration

Vanderbilt University investigators have discovered a new molecular mechanism that regulates microtubule dynamics. The unexpected finding, reported in Developmental Cell, has implications for cancer drug discovery.
By Leigh MacMillan
December 13, 2013

Manager of mitotic stress

The protein CK1 delays cell division to avoid the generation of defects that drive tumorigenesis.
By Leigh MacMillan
November 7, 2013

VU study sheds new light on DNA replication

David Cortez, Ph.D., and his Vanderbilt colleagues report new findings that shed light on fundamental processes involved in DNA replication and have implications for cancer therapies that target these processes.
By Leigh MacMillan
October 25, 2013

Targets of SIN drive cell division

Vanderbilt researchers have identified a key regulator of cell division.
By Leigh MacMillan
July 29, 2013

Motor protein revs up cell division

A motor protein that helps drive cell division may be a promising new target for cancer therapeutics.
By Leigh MacMillan
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