Cell Reports Archive — Page 1 of 4

Heather Pua, MD, PhD, and Neil Sprenkle, PhD, have discovered a protective role for microRNAs in immune cell macrophages during obesity, potentially opening new therapeutic avenues.
September 5, 2023

MicroRNAs in immune cells help protect against metabolic defects in obesity: study

Vanderbilt researchers have demonstrated that a cluster of microRNAs — small pieces of RNA that regulate gene expression — work in a type of immune cells called macrophages to help protect against metabolic defects in obesity.

Head-and-shoulders portrait of a smiling man wearing a purple plaid shirt over a white T-shirt.
February 2, 2023

Discovery of “cross-reactive” antibodies could aid treatment of viral co-infections

Top-view arrangement of potassium-rich foods on a blue wooden surface, including bananas, avocado, potatoes, mushrooms, tomatoes, broccoli, grapefruit, kiwi, carrots, nuts, beans, and a bowl of dried fruit.
January 19, 2023

Low potassium injures kidney

Vanderbilt researchers have discovered that low dietary potassium causes direct kidney injury, suggesting potential new targets for treating chronic kidney disease.

January 12, 2023

Antibody “fingerprinting” method potential advance to slow spread of dengue

Vanderbilt researchers have reported a major advance in understanding and potentially preventing dengue, a devastating, mosquito-borne tropical viral infection that is spreading across the globe.

Illustration of overlapping purple spherical cells, each with a prominent blue spherical nucleus, against a black background.
September 8, 2022

Immune cells drive beta cell loss in Type 2 diabetes

Vanderbilt researchers have discovered details of pancreatic beta cell loss — and potential therapeutic targets — during conditions of overnutrition, as occurs in obesity.

Young woman in a plaid shirt covers her mouth with one hand while clutching her abdomen with the other, appearing nauseated or unwell.
January 13, 2022

Salmonella overcomes host resistance

The invading pathogen Salmonella, a common cause of food poisoning, can change its metabolism to overcome host resistance to its colonization.