colitis

July 19, 2018

Novel insights on “leaky” gut

A protein involved in binding cells together helps maintain the integrity of the intestinal mucosa and plays a protective role in ulcerative colitis.

By Niyati Vachharajani
February 11, 2016

Study identifies potential colon cancer biomarker

A protein that suppresses a key cancer pathway in the colon may be a potential biomarker for colitis-associated tumors, researchers at Vanderbilt University Medical Center reported last month in the journal Gut.

By Bill Snyder
July 23, 2015

Study explores protein’s role in inflammation-associated cancer

An antioxidant protein may protect against colon cancer that develops in patients with inflammatory bowel disease, suggesting new strategies for reducing colon cancer risk in these patients.

By Leigh MacMillan
January 28, 2015

New clue to a devastating disease

New findings suggest a previously unrecognized role for the Sox10 transcription factor in Hirschsprung’s disease, and may lead to improved diagnostic and therapeutic approaches for this disease.

By Bill Snyder
April 25, 2014

Increased cell permeability may protect from colitis

Having a “leaky” gut may protect against colitis, a paradoxical finding that alters understanding of the role of cell permeability in intestinal homeostasis and immune regulation.

By Leigh MacMillan
March 1, 2013

Target for inflammatory bowel disease

The factor STAT6 appears to play a role in the pathogenesis of an inflammatory bowel disease, suggesting it may be a promising target for new treatments.

By Leigh MacMillan
April 6, 2012

Plant compound quells inflammation

Berberine, an herbal remedy for diarrhea and intestinal parasites, may be an effective treatment for gastrointestinal inflammatory diseases.
By Leigh MacMillan
October 27, 2011

Stopping colitis, STAT

Study suggests a new therapeutic target in ulcerative colitis.
By VUMC News and Communications