colon cancer

July 2, 2018

SMAD4 clue to colon cancer

Loss of a gene that is part of the TGF-beta signaling pathway increased inflammation in the colon and was observed in half of human colitis-associated cancers.

By Bill Snyder
October 18, 2017

Calcium intake and colorectal cancer

Calcium intake appears to protect against colorectal cancer in individuals with certain gene variants, Vanderbilt researchers have discovered.

By Leigh MacMillan
October 17, 2017

Researchers find novel mechanism of resistance to anti-cancer drugs

Vanderbilt investigators have discovered a novel non-genetic cause of resistance to the targeted anti-cancer therapy cetuximab. Their findings, reported this week in Nature Medicine, suggest a strategy for overcoming this resistance.

By Leigh MacMillan
bacteria microbiome
July 5, 2017

Bile acids, microbiota and colon cancer

Bile acids produced by a western diet alter the composition of the gut microbiota and promote intestinal carcinogenesis.

By Leigh MacMillan
December 8, 2016

Study links lifestyle factors to formation of high-risk polyps

Lifestyle factors like cigarette smoking and red meat consumption are known to be associated with an increased risk of colon polyps that can lead to colorectal cancer.

By VUMC News and Communications
July 25, 2016

Colon cancer awareness event set for Aug. 5

For some people cancer, especially colon cancer, is a persistent and potentially deadly visitor affecting family members from one generation to the next. Individuals who have a parent, sibling or child diagnosed with colon cancer have double the risk of developing the disease.

By VUMC News and Communications
March 24, 2016

Singer’s concert honors care received at Cancer Center

A cancer patient’s gratitude toward his Vanderbilt-Ingram Cancer Center (VICC) physician led to a star-studded concert to benefit the Cancer Center.
By VUMC News and Communications
February 18, 2016

Study explores less invasive way to monitor colorectal cancer

Investigators at Vanderbilt University Medical Center have published research regarding an important feature of colorectal cancer (CRC) that could eventually lead to the development of non-invasive means of monitoring cancer progression. After lung cancer, CRC is the second-most lethal cancer in the United States.
By VUMC News and Communications
February 11, 2016

Study identifies potential colon cancer biomarker

A protein that suppresses a key cancer pathway in the colon may be a potential biomarker for colitis-associated tumors, researchers at Vanderbilt University Medical Center reported last month in the journal Gut.
By Bill Snyder
July 23, 2015

Study explores protein’s role in inflammation-associated cancer

An antioxidant protein may protect against colon cancer that develops in patients with inflammatory bowel disease, suggesting new strategies for reducing colon cancer risk in these patients.
By Leigh MacMillan
February 9, 2015

Gene profile predicts metastasis

A specific gene expression profile represents a novel, biologically relevant “signature” for identifying colon cancers with high risk of metastatic recurrence, Vanderbilt researchers have found.
By Yan Su
August 26, 2013

Tumor factor spurs blood vessel growth

A newly identified factor regulates blood vessel growth in colorectal tumors and could be a promising target for cancer therapies.
By Leigh MacMillan
August 1, 2013

‘Undy’ event to raise colon cancer funds, awareness

Vanderbilt will add a new race event, the 2013 Nashville Undy 5000, to the list of affiliated events for the upcoming fall season.
By VUMC News and Communications