colon cancer

SMAD4 clue to colon cancer

Loss of a gene that is part of the TGF-beta signaling pathway increased inflammation in the colon and was observed in half of human colitis-associated cancers.

Calcium intake and colorectal cancer

Calcium intake appears to protect against colorectal cancer in individuals with certain gene variants, Vanderbilt researchers have discovered.

Researchers find novel mechanism of resistance to anti-cancer drugs

Vanderbilt investigators have discovered a novel non-genetic cause of resistance to the targeted anti-cancer therapy cetuximab. Their findings, reported this week in Nature Medicine, suggest a strategy for overcoming this resistance.

bacteria microbiome

Bile acids, microbiota and colon cancer

Bile acids produced by a western diet alter the composition of the gut microbiota and promote intestinal carcinogenesis.

Study links lifestyle factors to formation of high-risk polyps

Lifestyle factors like cigarette smoking and red meat consumption are known to be associated with an increased risk of colon polyps that can lead to colorectal cancer.

Free colon cancer awareness event is Aug. 5

For some people, cancer—especially colon cancer—is a persistent and potentially deadly visitor affecting family members from one generation to the next. Vanderbilt-Ingram Cancer Center, in partnership with the Colon Cancer Alliance, is hosting a free seminar to educate the public about risk factors associated with the disease.

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