coma

Interventions such as daily spontaneous waking trials can help patients avoid injuries associated with intensive care.

AI predicts next-day delirium or coma in ICU patients

A team at Vanderbilt University Medical Center used machine learning to predict the likelihood of next-day brain function status changes in critical care patients.

Risk factors for delirium

High levels of blood markers for vascular endothelial dysfunction were associated with longer periods of confusion in ICU patients, Vanderbilt researchers have discovered.

A role for blood vessels in delirium?

Dysfunction of the endothelial cells that line blood vessels may contribute to delirium and coma in critically ill patients – and could be a target for therapy.

Pathways to delirium in the ICU

Study suggests that the “kynurenine” biochemical pathway could be a target for reducing delirium and coma in critically ill patients.