Department of Pediatrics

Delirium, benzos and the pediatric ICU

With other risk factors held equal, children who received a benzodiazepine sedative drug were nearly three times more likely to experience delirium – confused thought – the following day.

Pediatric health conditions, their treatments and the related stress hinder the prefrontal cortex, which is the region of the brain associated with learning, memory and behavior. (istock)

Goal of new tissue-chip research is to assess efficacy of novel epilepsy drugs

An interdisciplinary team of Vanderbilt University researchers has received a two-year, $2-million federal grant to develop an “organ-on-chip” model for two genetic forms of epilepsy.

Address highlights Pediatrics’ people, progress, growth

Steven Webber, MBChB, MRCP, delivered the annual State of the Department of Pediatrics address on Tuesday, with growth and quality improvement serving as recurring themes along with a focus on the department’s four mission areas — discovery, clinical care, education and advocacy, service and community partnerships.

Doris Duke Foundation lauds Van Driest’s research

Sara Van Driest, M.D., Ph.D., who is developing methods for precision dosing of pediatric medications at Vanderbilt University Medical Center (VUMC), has received a 2017 Clinical Scientist Development Award from the Doris Duke Charitable Foundation.

bacteria microbiome

Bile acids, microbiota and colon cancer

Bile acids produced by a western diet alter the composition of the gut microbiota and promote intestinal carcinogenesis.

Team investigates antiviral that inhibits SARS, MERS

A new antiviral drug candidate inhibits a broad range of coronaviruses, including the SARS and MERS coronaviruses, a multi-institutional team of investigators reports this week in Science Translational Medicine.

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