DNA repair

July 16, 2015

Study reveals how protein helps cells tolerate DNA damage

Vanderbilt and Stanford investigators have discovered how a protein that’s part of the DNA replication “machinery” helps cells tolerate DNA damage.

By Leigh MacMillan

May 23, 2014

Repair protein’s DNA recognition motif

Insights into the workings of DNA damage response proteins such as SMARCAL1 could suggest new ways to improve genome integrity and prevent cancer.

By Leigh MacMillan

May 9, 2014

Bypassing DNA damage

Studies of a human polymerase that replicates DNA have provided a complete kinetic and structural framework for understanding how the enzyme accurately bypasses DNA damage.

By VUMC News and Communications

November 7, 2013

VU study sheds new light on DNA replication

David Cortez, Ph.D., and his Vanderbilt colleagues report new findings that shed light on fundamental processes involved in DNA replication and have implications for cancer therapies that target these processes.

By Leigh MacMillan

March 19, 2012

iPOND method goes fishing for proteins

A new tool will allow researchers to identify proteins involved in DNA replication and damage repair, processes that go awry in cancer.

By Leigh MacMillan