Regulation of the enzyme Sirtuin 1 in blood vessel endothelial cells may drive altered metabolism and vascular dysfunction during sepsis, Vanderbilt researchers have discovered.
Insight into the pathophysiology of an enigmatic and debilitating disease suggests new treatment approaches.
High levels of blood markers for vascular endothelial dysfunction were associated with longer periods of confusion in ICU patients, Vanderbilt researchers have discovered.
Increased activity of the “fight or flight” nervous system contributes to obesity-associated hypertension and may be a good therapeutic target for the disease.
Endothelial cells residing in the coronary arteries can function as cardiac stem cells to produce new heart muscle tissue, Vanderbilt University investigators have discovered.
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