FASEB Journal

New tools to combat kidney fibrosis

Vanderbilt investigators have developed a new mouse model of kidney fibrosis, which provides a platform for identifying new targets and treatment strategies.

Healing without scarring

Drugs that inhibit the Wnt signaling pathway can regenerate injured skin and may be useful in treating fibromatosis, degenerative joint disease and cancer.

Protein interaction protects against neurodegeneration

Two proteins interact to maintain selenium levels in the brain, and protect neurons from degeneration.

Protein repairs esophageal DNA damage

A protein involved in repairing DNA damage associated with gastric reflux may play a tumor suppressor role in the esophagus and could represent a target for therapies to combat esophageal cancer.