germline

Early-onset CRC germline genetic differences identified by race, ethnicity

A Vanderbilt study that delved into genetic predisposition for early-onset colorectal cancer by race and ethnicity has identified differing germline risk variants.

Vanderbilt Prize winner Doudna advocates caution in human germline editing

It is now possible to “edit” the human germline — the genetic cargo carried in sperm and eggs and which is passed to the next generation — in a way that snips out the mutations which cause inherited disease.