GPCR

April 11, 2019

The arrestin-GPCR connection

Understanding details of how arrestins deactivate signaling by G-protein coupled receptors is key to the design of new therapeutics aimed at these cellular “inboxes” that are targeted by up to half of all pharmaceuticals.

By Sanjay Mishra
March 29, 2018

Nobel laureate Kobilka set to deliver Flexner Discovery Lecture on April 5

Brian Kobilka, MD, who shared the 2012 Nobel Prize in Chemistry for his studies of G protein-coupled receptors (GPCRs), will deliver the next Flexner Discovery Lecture on April 5.

By Leigh MacMillan
January 23, 2015

New view of dopamine heteromers

Although heteromeric dopamine receptors composed of both D1 and D2 subunits have been proposed to play a role in depression and schizophrenia, recent studies suggest these heteromers do not exist.

By VUMC News and Communications
October 24, 2013

Shining a light on night blindness

Vanderbilt researchers are studying how mutations in the receptor for light, rhodopsin, cause light blindness.

By VUMC News and Communications
January 18, 2013

Seeing light receptor’s interactions

Understanding how the main receptor for light interacts with other signaling molecules may inform new pharmaceutical development.

By Leigh MacMillan
October 18, 2012

Nobel in Chemistry reveals VU ties that bind

Several Vanderbilt researchers have collaborated with this year’s Nobel Chemistry winners.

By Bill Snyder